| Version | Release Date | Changes |
|---|---|---|
| COPASI 4.27 (Build 217) | September 14, 2019 | changelog |
| COPASI 4.26 (Build 213) | July 31, 2019 | changelog |
| COPASI 4.25 (Build 207) | March 15, 2019 | changelog |
| COPASI 4.24 (Build 197) | July 30, 2018 | changelog |
| COPASI 4.23 (Build 184) | April 18, 2018 | changelog |
| COPASI 4.22 (Build 170) | November 10, 2017 | changelog |
| COPASI 4.21 (Build 166) | October 9, 2017 | changelog |
| COPASI 4.20 (Build 158) | July 31, 2017 | changelog |
| COPASI 4.19 (Build 140) | January 12, 2017 | changelog |
| COPASI 4.18 (Build 136) | November 28, 2016 | changelog |
| COPASI 4.17 (Build 135) | November 21, 2016 | changelog |
| COPASI 4.16 (Build 104) | August 19, 2015 | changelog |
| COPASI 4.15 (Build 95) | March 4, 2015 | changelog |
| COPASI 4.14 (Build 89) | Oct 10, 2014 | changelog |
| COPASI 4.13 (Build 87) | Aug 14, 2014 | changelog |
| COPASI 4.12 (Build 81) | Apr 18, 2014 | changelog |
| COPASI 4.11 (Build 65) | Oct 25, 2013 | changelog |
| COPASI 4.11 (Build 64) | Sept 30, 2013 | changelog |
| COPASI 4.10 (Build 55) | May 16, 2013 | changelog |
| COPASI 4.9.45 (Development) | January 20, 2013 | changelog |
| COPASI 4.8 (Build 35) | December 20, 2011 | changelog |
| COPASI 4.7 (Build 34) | July 13, 2011 | changelog |
| COPASI 4.6.33 (development) | October 10, 2010 | changelog |
| COPASI 4.6 (Build 32) | July 21, 2010 | changelog |
| COPASI 4.5.31 (development) | March 18, 2010 | changelog |
| COPASI 4.5 (Build 30) | April 15, 2009 | changelog |
| COPASI 4.4.29 (development) | January 5, 2009 | changelog |
| COPASI 4.4.28 (development) | December 5, 2008 | changelog |
| COPASI 4.4.27 (development) | August 20, 2008 | changelog |
| COPASI 4.4 (Build 26) | Mai 8, 2008 | changelog |
| COPASI 4.3 (Build 25) | March 12, 2008 | changelog |
| COPASI 4.2.24 (development) | January 9, 2008 | changelog |
| COPASI 4.2.23 (development) | September 28, 2007 | changelog |
| COPASI 4.2 (Build 22) | July 24, 2007 | changelog |
| COPASI 4.1 (Build 21) | May 10, 2007 | changelog |
| COPASI 4.0.20 (development) | February 9, 2007 | changelog |
| COPASI 4.0.19 (development) | October 6, 2006 | changelog |
| COPASI 4.0 (Build 18) | June 16, 2006 | changelog |
| COPASI (4.0 Build 17 RC 1) | February 15, 2006 | changelog |
| COPASI (4.0 Build 15 test version) | September 15, 2005 | changelog |
| COPASI (4.0 Build 14 test version) | August 30, 2005 | changelog |
| COPASI (4.0 Build 13 test version) | April 28, 2005 | changelog |
| COPASI (4.0 Build 12 test version) | Feb. 18, 2005 | changelog |
| COPASI (4.0 Build 11 test version) | Dec. 19, 2004 | changelog |
| COPASI (4.0 Build 10 test version) | Nov. 4, 2004 | changelog |
| COPASI (4.0 Build 9 test version) | Oct. 11, 2004 | changelog |