This release features new 64 bit packages for all supported platforms.
Graphical User Interface (CopasiUI)
Enhanced parsing of mathematical expression to allow the comparison operator <, <=, >, >=, and == as well as the Boolean operators || and &&.
Allowed calculation results to be selected as constraints for optimization and parameter estimation.
Improved display of mass conservation results. The moieties are now displayed in amount if the user is in the concentration framework.
Added Update Model button to the optimization result widget
Simulation Engine
The calculation of statistics is no optional for optimization and parameter estimation tasks.
Start values can no be randomized automatically for optimization and parameter estimation tasks.
SBML
Added support for constant conversion factors in Level 3.
Bug Fixes since COPASI 4.6.33 (development)
Graphical User Interface (CopasiUI)
Fixed crash when editing notes and switching the view mode.
Fixed display of rate law interpretation in the model.
The model name no longer appears in the left navigation tree.
Fixed write access to the example directory so that users are able to execute them.
Fixed opening of files which included non-ascii characters in the name through double click under Windows
Allowed calculation results to be selected as constraints for optimization and parameter estimation.
Deleting functions now prompts the user if the function is used within the model.
Improved editing behavior in tables for compartments, species, global, quantities and reactions.
Boolean values in tables are now represented by check boxes.
Preserved line breaks and indents in notes when free text and not XHTL is used.
Fixed problem editing particle numbers when in the particle number framework.
All numerical values are now displayed and edited with 10 significant digits.
Prevent crashes caused by incomplete specification of kinetic parameters or modifiers.
Fixed editing of event assignments to trigger update the internal dependencies.
Fixed erroneous empty error messages at the end the steady state calculation.
Improved MathML and rendering of build in functions like sin, cos, ceil(), and floor().
Fixed deletion of multiple objects which could cause a crash in COPASI.
Improved handling of MIRIAM resource Ids, leading and trailing spaces are now stripped automatically.
Simulation Engine
Fixed crash in hybrid stochastic simulation method occurring for some models
Fixed event detection to correctly deal with saddle points which have value 0.
Fixed output of time course for models with events which did not distinguish between equality and inequality when an event occurred at the end of an integration intervall.
Fixed occasional problem when calculating the steady-state for models with moieties for which the dependent species amount is 0.
Improves sensitivities task to handle failed subtasks gracefully. COPASI will report a warning when more than 20% of the subtasks fail.
Fixed parameter estimation to work correctly with model or experimental data containing changes to the volume.
Improved handling of experimental data files not located in the same directory as the COPASI file.
SBML
Fixed SBML export of initial assignment for species for which the hasOnlySubstance flag is set.
Fixed import of piecewise defined functions which are missing an otherwise construct.
Fixed export of render extension information.
Improved import of models containing initial assignments for species which in rare circumstances where not executed.
