The COPASI team announces the immediate availability of the stable release COPASI 4.43 (Build 288).

A new release of COPASI has been made available. Please visit our free download page to retrieve this latest development release. Please note this version is released under the Artistic License 2.0, which is an OSI approved license. This license allows non-commercial and commercial use free of charge.

Release Date: July 08, 2024

Bug Fixes

• Command Line (CopasiSE)
  • No files are created or modified when the option –validate is given.
• Simulation Engine
  • Time Course Task: The methods RADAU5 now correctly supports the option Suppress Output Before …
  • Time Course Task: The hybrid methods Hybrid LSODA & Hybrid Runge-Kutta now supports automatic step size correctly.
  • Optimization and Parameter Estimation Tasks: The method Praxis now correctly terminates if the if solution is within the tolerance.
  • Parameter Estimation Task: The Method Evolution Strategy (SRES) now checks the functional constraints like other methods.
  • Metabolic Control Analysis and Linear Noise Approximation Tasks: The result now contains the Steady-State result.

More information can be found in the changelog.