These error messages can occur when running a trajectory task. All of them depend on the method that has been chosen for the trajectory, e.g. stochastic, since the error message is generated by the method and not the task itself.
Identifier
CTrajectoryMethod (1)
Message
Hybrid simulation not applicable, since the stoichiometry contains a non-integer.
Description
Hybrid simulations can not be run on models that contain reactions with non integer stoichiometries.
Identifier
CTrajectoryMethod (2)
Message
Hybrid simulation not applicable, since reversible reactions exists.
Description
Hybrid simulations can not be run on models with reversible reactions. You can try to convert all reactions to irreversible reactions via the "Convert to irreversible" menu item in the tools menu.
Identifier
CTrajectoryMethod (3)
Message
Hybrid simulation not applicable, since more than one compartment is involved.
Description
Hybrid simulations only work on single compartment models.
Identifier
CTrajectoryMethod (4)
Message
Lower Limit 'LOWERLIMIT' is greater than Upper Limit 'UPPER LIMIT'.
Description
Check the limits for the hybrid method. The LOWERLIMIT parameter has to be smaller than the UPPERLIMIT parameter.
Identifier
CTrajectoryMethod (6)
Message
Deterministic integration failed. LSODA reported:LSODA_ERROR_MESSAGE Please see result for indications of numerical instability.
Description
The deterministic integration failed. This is a strong indication of numerical problems. A look at the time series calculated up to the point the problem occurred is often helpful in resolving the problem.
Identifier
CTrajectoryMethod (7)
Message
Problem is not set.
Description
INTERNAL
Identifier
CTrajectoryMethod (8)
Message
Problem is not a trajectory problem.
Description
INTERNAL
Identifier
CTrajectoryMethod (9)
Message
Negative time steps not possible with stochastic simulation.
Description
The duration of the trajectorytime course is negative. This is not allowed for stochastic integration.
Identifier
CTrajectoryMethod (10)
Message
The tau-Leap Method encountered numerical problems. You can try to reduce the tau-value.
Description
Choose a lower value for tau and rerun the time course task.
Identifier
CTrajectoryMethod (11)
Message
Invalid tau-value ('TAU'). Tau must have a positive value.
Description
Values for tau must be positive numbers.
Identifier
CTrajectoryMethod (12)
Message
Internal step limit exceeded.
Description
The internal step limit is exceeded. Reducing the accuracy requirements or increasing the step limit may resolve the problem.
Identifier
CTrajectoryMethod (13)
Message
Runge Kutta Step size must be positive in hybrid method.
Description
The stepsize for the Runge Kutta solver within the hybrid method must be positive, since the hybrid method does not support backward integration in time.
Identifier
CTrajectoryMethod (14)
Message
Use Random Seed should be 0 or 1 since it is a boolean parameter.
Description
The value of the parameter called "Use Random Seed" should be 0 or 1 since it is a boolean parameter.
Identifier
CTrajectoryMethod (15)
Message
Max Internal Steps needs to be positive.
Description
The maximal number of internal steps must be at least 1.
Identifier
CTrajectoryMethod (16)
Message
Numerical Error encountered.
Description
!!!UNDOCUMENTED!!!
Identifier
CTrajectoryMethod (17)
Message
At least one reaction is necessary to perform stochastic simulation.
Description
!!!UNDOCUMENTED!!!
Identifier
CTrajectoryMethod (18)
Message
The model contains a global quantity with an ODE rule. Stochastic simulation is not possible.
Description
!!!UNDOCUMENTED!!!
Identifier
CTrajectoryMethod (19)
Message
The model contains a global quantity with an assignment rule. The value of the quantity is used in the model. Stochastic simulation of such models is not possible with this version of COPASI.
Description
!!!UNDOCUMENTED!!!
Identifier
CTrajectoryMethod (20)
Message
The model contains a species with an ODE rule. Stochastic simulation is not possible.
Description
!!!UNDOCUMENTED!!!
Identifier
CTrajectoryMethod (21)
Message
The model contains a compartment with an ODE rule. Stochastic simulation is not possible.
