Support of initial assignments for compartments, metabolites, and global quantities.
Two new optimization methods Truncated Newton and Praxis.
The switch between the display of concentrations or particle numbers is now conveniently located in the tool bar.
Bug Fixes
Fixed problem in the model analyzer which lead to incorrect classification of reversible kinetic laws.
The trajectory task is now able to integrate models, which do not contain any reactions and ODEs
Fixed problem in steady state calculation for models with changing volumes.
Steady State calculation may have returned negative particle numbers or volumes though the user opted to exclude such states.
Improved the GUI for the Steady State result to include a list of compartments.
Corrected error in the optimization method Steepest Decent, which only occurred in optimization but not in parameter estimation.
Enhanced the randomization of start values for large intervals containing 0.
Corrected problem in which COPASI overwrote existing files though the user chose to cancel the saving or export process.
Improved error and warning messages created during SBML import.
Fixed crash occurring in models imported from SBML, which used functions that contained special character such as * and + in the variable names.
Fixed problem loading SBML files containing functions which listed more arguments than where used in the function.
Improved handling of units when importing SBML to support a wider range of models.
Known Issues
In rare occasion COPASI may crash during SBML import. This is due to some problems in libsbml from which COPASI is not able to recover. If you encounter such a problem please contact us as we are working with the libsbml team to correct these issues and any feedback will accelerate the process.
