COPASI's Use In Toxicology

2021
King J, Mihaila SM, Ahmed S, Truckenmüller R, Giselbrecht S, Masereeuw R, Carlier A (2021) The Influence of OAT1 Density and Functionality on Indoxyl Sulfate Transport in the Human Proximal Tubule: An Integrated Computational and In Vitro Study. Toxins 13:674 Toxicology Physiology Link

1 publication
2020

0 publication
2019

0 publication
2018
Coulthard SA, McGarrity S, Sahota K, Berry P, Redfern CP (2018) Three Faces of Mercaptopurine Cytotoxicity in vitro: Methylation, Nucleotide Homeostasis and Deoxythioguanosine in DNA. Drug Metabolism and Disposition 46:1191–1199 Toxicology Biochemistry Link
Leedale J, Sharkey KJ, Colley HE, Norton ÁM, Peeney D, Mason CL, Sathish JG, Murdoch C, Sharma P, Webb SD (2018) A Combined In Vitro/In Silico Approach to Identifying Off-Target Receptor Toxicity. iScience 4:84–96 Toxicology Link

2 publications
2017
Hendrickx DM, Souza T, Jennen DG, Kleinjans JC (2017) DTNI: a novel toxicogenomics data analysis tool for identifying the molecular mechanisms underlying the adverse effects of toxic compounds. Archives of Toxicology 91:2343–2352 Computational Method Toxicology Link

1 publication
2016

0 publication
2015
Amemiya T, Honma M, Kariya Y, Ghosh S, Kitano H, Kurachi Y, Fujita K, Sasaki Y, Homma Y, Abernethy DR, Kume H, Suzuki H (2015) Elucidation of the molecular mechanisms underlying adverse reactions associated with a kinase inhibitor using systems toxicology. npj Systems Biology and Applications 1:15005 Toxicology Signaling Link
Gladkovskaya O, Greaney P, Gun'ko YK, O'Connor GM, Meere M, Rochev Y (2015) An experimental and theoretical assessment of quantum dot cytotoxicity. Toxicology Research 4:1409-15 Toxicology Link
Tóth A, Brózik A, Szakács G, Sarkadi B, Hegedüs T (2015) A Novel Mathematical Model Describing Adaptive Cellular Drug Metabolism and Toxicity in the Chemoimmune System. PLOS One 10:e0115533 Toxicology Link

3 publications
2014
Talemi SR, Jacobson T, Garla V, Navarrete C, Wagner A, Tamás MJ, Schaber J (2014) Mathematical modelling of arsenic transport, distribution and detoxification processes in yeast. Molecular Microbiology 92:1343–1356 Toxicology Metabolism Link

1 publication
2013
Geenen S, du Preez FB, Snoep JL, Foster AJ, Sarda S, Kenna JG, Wilson ID, Westerhoff HV (2013) Glutathione metabolism modeling: a mechanism for liver drug-robustness and a new biomarker strategy. Biochimica et Biophysica Acta 1830:4943- 59 Toxicology Metabolism Link
van't Erve TJ (2013) Discoveries on the storage of red blood cells and the exposure of cells in culture to xenobiotics. D.Phil. Thesis, The University of Iowa Toxicology Link

2 publications
2012

0 publication
2011
Chen X (2011) Glutathione suppresses the autoxidation of 2’,5’-dihydroxy-4-chlorobiphenyl. MS Thesis, University of Iowa. Toxicology Link

1 publication
2010

0 publication
2009
Shi Y, Varghese SM, Huang S, White J, Pervaiz S, Tucker-Kellogg L (2009) Computational modeling of pathway dynamics for detecting drug effects: paradoxical effects of LYS303511 on TRAIL-induced apoptosis. Proceedings of the LSS Computational Systems Bioinformatics Conference 213–224 Toxicology Link

1 publication
2008

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2007

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2006

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